Important Safety Information
Effective date: July 7, 2026
The following Important Safety Information applies to THIN™, THIN-R™, and THIN-ST™, which contain GLP-1 receptor agonist medications (semaglutide or tirzepatide). This information is provided by Healthy Sprays LLC for general education only. It is not complete, it is not medical advice, and it is not a substitute for the guidance of your treating provider or the instructions dispensed with your medication. Always talk with a licensed healthcare provider before starting, stopping, or changing any medication.
Compounded & Not FDA-Approved
THIN™, THIN-R™, and THIN-ST™ are compounded, prescription-only medications prepared by state-licensed compounding pharmacies for an individual patient pursuant to a valid prescription. Compounded drugs are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or manufacturing quality. They are dispensed only if an independent licensed provider determines treatment is medically appropriate for you.
Warning: Risk of Thyroid C-Cell Tumors
In studies, medications in the GLP-1 receptor agonist class (which includes semaglutide and tirzepatide) caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in rodents. It is not known whether these medications cause thyroid C-cell tumors, including MTC, in humans.
Do not use these products if you or a family member has ever had medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your provider right away if you develop a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath — these may be symptoms of thyroid cancer.
Do Not Use These Products If:
- You are pregnant, planning to become pregnant, or breastfeeding.
- You or a family member has a personal or family history of medullary thyroid carcinoma (MTC), or you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- You have type 1 diabetes.
- You have had a serious hypersensitivity (allergic) reaction to semaglutide or tirzepatide or to any ingredient in the product.
- You have severe gastrointestinal disease, including gastroparesis (delayed stomach emptying).
- You have a history of pancreatitis.
- You have significant kidney impairment or kidney disease.
This list is not exhaustive. Share your complete health history with your provider so they can determine whether treatment may be appropriate for you.
Talk to Your Provider First If:
- You take diabetes medications, especially insulin or sulfonylureas — combining them with a GLP-1 medication may increase the risk of low blood sugar (hypoglycemia), and your doses may need adjustment and monitoring.
- You have diabetic retinopathy or other eye problems related to diabetes — rapid improvement in blood sugar has been associated with a temporary worsening of retinopathy in some patients.
- You have or have had gallbladder disease (such as gallstones) — GLP-1 medications have been associated with gallbladder problems.
- You have any other medical conditions or take any other medications, vitamins, or supplements.
Common Side Effects
Like other GLP-1 medications, these products may cause side effects. The most commonly reported are gastrointestinal and are often most noticeable when starting treatment or increasing a dose. They may include:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal (stomach) pain
- Headache
- Fatigue
These are not all of the possible side effects. Tell your provider about any side effect that bothers you or does not go away.
Serious Warning Signs — Seek Medical Care
Stop use and seek medical care promptly if you experience any of the following:
- Severe abdominal pain, with or without vomiting, that does not go away — it may radiate to your back and may be a symptom of pancreatitis.
- Persistent vomiting or diarrhea leading to dehydration — dehydration can worsen kidney problems.
- Vision changes, such as blurred vision or other changes in eyesight.
- Signs of an allergic reaction, such as rash, itching, swelling of the face, lips, tongue, or throat, rapid heartbeat, or trouble breathing.
- Symptoms of gallbladder problems, such as pain in the upper right abdomen, fever, yellowing of the skin or eyes, or clay-colored stools.
- Symptoms of low blood sugar (especially if you also take insulin or a sulfonylurea), such as shakiness, sweating, confusion, dizziness, or rapid heartbeat.
Drug Interactions
GLP-1 medications slow stomach emptying, which may affect how quickly other oral medications are absorbed. This may matter for medicines where timing or blood levels are important — for example, certain oral contraceptives, thyroid medications, or narrow-therapeutic-index drugs. Tell your provider and pharmacist about all prescription and over-the-counter medications, vitamins, and supplements you take, and do not combine these products with other GLP-1 or weight-management medications unless your provider directs you to.
Storage & Handling
- Store at room temperature unless the label or your pharmacy directs otherwise.
- Keep the spray out of reach of children and pets.
- Do not use the product past the beyond-use date on the pharmacy label, and do not use it if it appears discolored or contaminated.
- Follow the specific storage, handling, and disposal instructions provided by your dispensing pharmacy — they control for your specific preparation.
Reporting Adverse Events
If you experience a side effect or adverse event, contact your treating provider through PrescriberNow and seek medical attention as needed. You may also notify Healthy Sprays LLC at cs@healthysprays.com. You are encouraged to report adverse events involving medications to the FDA's MedWatch program at 1-800-FDA-1088 or online at fda.gov/medwatch.
In an emergency, call 911
If you have signs of a serious or life-threatening reaction — such as trouble breathing; swelling of the face, lips, tongue, or throat; severe abdominal pain; or loss of consciousness — call 911 or go to the nearest emergency room immediately.
This summary does not list all possible risks, side effects, or interactions. Only a licensed provider, after reviewing your health history, can determine whether a GLP-1 medication may be appropriate for you. See also our Telehealth & Provider Review Notice, Terms of Service, and Accessibility statement.
Prepared for Healthy Sprays LLC. This document is provided for general informational purposes; consult your licensed healthcare provider for medical advice.